Switch to CUVRIOR

Talk to your healthcare provider to see  if CUVRIOR is the right maintenance treatment for you.

Consider switching to CUVRIOR and explore  on-the-go potential

CUVRIOR offers convenient twice-daily dosing and is stable at room temperature, so it doesn’t require refrigeration.

Dosing & Administration

Convenient twice-daily dosing for long-term  maintenance therapy.

If you're switching from another trientine formulation to CUVRIOR, please note that the doses are different.

Take CUVRIOR on an empty stomach:

at least 1 hour before meals
or 2 hours after meals
at least 1 hour apart from any other food, milk, or oral medication
swallow tablets without crushing, chewing, or dissolving tablets

Supplied in a portable blister pack

Tablets are scored so they can be divided in half  if needed.

Tablets are smaller than most other  maintenance options.

Talk to your doctor about CUVRIOR

Download the CUVRIOR discussion guide and explore your reasons for wanting to switch.

Learn more about CUVRIOR

Do not use CUVRIOR if you are allergic to trientine or any of the ingredients in CUVRIOR. Your WD symptoms may worsen when starting treatment because of the rapid removal of copper from your body. Call your doctor if your symptoms worsen.

Interested in financial assistance or insurance support?

The Navigator Program™ could help

The Navigator Program™ is a no cost program available to CUVRIOR patients that provides access support.

Explore Patient Support

INDICATION

CUVRIOR is a prescription medicine used to treat adults with stable Wilson Disease who are de-coppered and able to take penicillamine. Wilson Disease is a condition where the body stores too much copper. CUVRIOR is a chelating medicine which binds copper in the blood stream and eliminates it in the urine to help reduce excess copper in the organs.

IMPORTANT SAFETY INFORMATION

Do not use CUVRIOR if you are allergic to trientine or to any of the ingredients in CUVRIOR.
Your Wilson Disease symptoms could get worse when you start treatment. This could happen because too much copper is removed from the body in a short period of time. Your doctor may need to reduce your dose or stop CUVRIOR treatment.
Copper deficiency may develop following treatment with CUVRIOR. Your doctor will do tests to monitor your urine and blood for copper.
Iron deficiency may develop while taking CUVRIOR. If this happens, your doctor may tell you to take iron supplements for a limited time.
Allergic reactions, such as a rash can occur. If a rash or other allergic reaction occurs, contact your doctor immediately or get emergency help.
The most common side effects are pain in the abdomen, change in bowel habits, rash, hair loss (alopecia), and mood swings.

Take CUVRIOR at least 1 hour apart from any other oral medicine. Tell your doctor about all the medicines you're taking, including over-the-counter medicines, vitamins, and herbal supplements. Avoid taking supplements when taking CUVRIOR. Taking CUVRIOR with mineral supplements (e.g., iron, zinc, calcium, magnesium) can reduce the effectiveness of CUVRIOR. If iron supplementation is necessary, take CUVRIOR at least 2 hours before or 2 hours after taking iron; for other mineral supplements (e.g., zinc, calcium, magnesium), take CUVRIOR at least 1 hour before or 2 hours after. Do not start or stop any medicines while taking CUVRIOR without talking to your doctor.

These are not all the possible side effects of CUVRIOR. You are encouraged to report negative side effects of prescription drugs. Contact Orphalan at 1-800-961-8320 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please see full Prescribing Information.

INDICATION

CUVRIOR is a prescription medicine used to treat adults with stable Wilson Disease who are de-coppered and able to take penicillamine. Wilson Disease is a condition where the body stores too much copper. CUVRIOR is a chelating medicine which binds copper in the blood stream and eliminates it in the urine to help reduce excess copper in the organs.

IMPORTANT SAFETY INFORMATION

Do not use CUVRIOR if you are allergic to trientine or to any of the ingredients in CUVRIOR.
Your Wilson Disease symptoms could get worse when you start treatment. This could happen because too much copper is removed from the body in a short period of time. Your doctor may need to reduce your dose or stop CUVRIOR treatment.
Copper deficiency may develop following treatment with CUVRIOR. Your doctor will do tests to monitor your urine and blood for copper.
Iron deficiency may develop while taking CUVRIOR. If this happens, your doctor may tell you to take iron supplements for a limited time.
Allergic reactions, such as a rash can occur. If a rash or other allergic reaction occurs, contact your doctor immediately or get emergency help.
The most common side effects are pain in the abdomen, change in bowel habits, rash, hair loss (alopecia), and mood swings.

Take CUVRIOR at least 1 hour apart from any other oral medicine. Tell your doctor about all the medicines you're taking, including over-the-counter medicines, vitamins, and herbal supplements. Avoid taking supplements when taking CUVRIOR. Taking CUVRIOR with mineral supplements (e.g., iron, zinc, calcium, magnesium) can reduce the effectiveness of CUVRIOR. If iron supplementation is necessary, take CUVRIOR at least 2 hours before or 2 hours after taking iron; for other mineral supplements (e.g., zinc, calcium, magnesium), take CUVRIOR at least 1 hour before or 2 hours after. Do not start or stop any medicines while taking CUVRIOR without talking to your doctor.

These are not all the possible side effects of CUVRIOR. You are encouraged to report negative side effects of prescription drugs. Contact Orphalan at 1-800-961-8320 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please see full Prescribing Information.